"Universum Medical - Holistic Medical Center
See an article two years ago, talk about the flaw that American medical research. Look to be able to ‘t help attacking a palm to had said afterwards. With the recognition level of this person, if give the position with above of director of department of science and technology of Ministry of Public Health the least, the development that can be Chinese medicine develops your work to use. Currently hold the post ofChen Zhu‘s minister to should have clear view to these problems.
Combine an earthquake to study the issue of the respect, with below the flaw that the American medicine that article place speaks of research has however almost identical with sameness place. If be like a few words medical instead earthquake, relevant content fills in with the knowledge of respective course correspondence and language, go up at all the blemish that those who talk also is the seismic research that the west is a delegate with the United States.
I think, the most hopeful implementation breaks through China, two course that take world front row are medicine learn to study with the earthquake, but there is tremendous resistance however in real progress, see the rich article that reprints below can understand somewhat. Study research medicine learns, go abroad after learning more than 10 years can somewhat awareness, write with respect to such good literary works, watch instead great majority still indulges nowadays in one-sided foreign science, only foreigner theory is from follow suit blindly, do not know " contradiction is talked " and " practice is talked " why content, see the error on road of not clear development and trap, of one mind research the seismic learned men that can conform only, when can you begin arousal?
Of course, here a bit what we still should see, present medicine develops the United States to be kidnapped by place of medical course of study, by medical industry profit drive or restrain, this decided its medicine and the course that concern with health develop a future. The productivity development of capitalist society progresses than the feudal society, development of socialistic society productivity also should progress than capitalist society. So, a serious problem is, good luck is to have, but it is good luck only after all, development whether get coming true, the condition that still pledges by sociality essentially produces the biggest conclusive effect effect.
The article brings from: Rich guest of Lei Juntao
Http://www.sciencenet.cn/m/user_content.aspx? Id=258621The good luck of the flaw that American medicine research and China
Ten years ago, the author resembles lots and lots of is opposite western science and technology fills the Chinese young person that adores piously same, left the motherland, begin career of oneself foreign jump the queue. Will profess to be chosen especially for god first child civilian Judaic nation-state - Israel assiduously research a doctor‘s degree, the powerful nation of science and technology that comes to date of so-called world above again next - the United States undertakes medicine research. What study abroad in abroad is inchoate, of the western medicine research technique that the author represents to be with the United States rigorous, of technical measure advanced, what learning discusses is active and special adore, think medicine of American type west research to representing the mankind to conquer the disease improves healthy hope. A when obtain in medical field place in biology in recent years another progress, be like the control of contagion, the organ transplants, test tube baby, clone life, a collection of illustrative plates of human gene group is finished, dry cell cure research to wait, the western medicine that makes the United States is a delegate again research by hood the flowery aureola of all-conquering. Make the person thinks to want to rely on western medicine research only, the mankind can conquer completely all diseases, include the chronic and stubborn disease of nowadays, be like heart disease, cancer, head apoplectic, AIDS.
As the elapse of time and the addition that oneself study experience, the author discovers western medicine research to be not people to imagine gradually in that way perfect is omnipotent. So far, it did not announce thoroughly already the mystery that disease happening develops, fail to be helped effectively to effect a radical cure the disease is offerred again. Centenary before the disease that cannot treat, cannot treat the disease that; China cannot treat likewise now, the United States also cannot be treated likewise. And the change as industrialized process and zoology environment, old disease has not received effective treatment, new disease appears ceaselessly again, study to this west medicine more appear ability not equal to one‘s ambition. Tell honestly, western medicine research is diagnosed to the disease and the prevention and cure of epidemic contagion made fruitful contribution. Clinical examine to be diagnosed technology of scanning of smooth fluoroscopy of technology, X, CT, nuclear magnetic resonance, vaccinal development for the disease with precaution control provided strong technical measure. But in the remedial respect of diseases of a lot of blame infection sex it is at a loss what to do however hopeless.
Since western medicine research to sending ill mechanism and clinical cure respect to do not have too great progress,people perhaps can ask, why meeting year after year adds human mean life, does healthy state also get ameliorative gradually? Not allow to oppugn, come nearly 160 years human mean life increased full 33 years old, from 1840 average 44 years old those who increase to 2000 is average 77 years old. The development of scientific progress and society, make of the mankind live environment and live quality gets ameliorative greatly, this is the main reason that human mean life increases. We know, the main factor that affects human mean life includes: Hurricane of? of foot of divide evenly brightness, big the) such as waterlogged, earthquake, arid, famine, war, pestilential (epidemic contagion) with common disease. Technology progress reduced natural disaster greatly the hasten of society of harm; mankind to the mankind reduced large-scale war at reason erupt the happening that the development of; medicine diagnostic technology and antibiotic and vaccinal invention controlled epidemic epidemic effectively, make disease of most infection sex is able to treat. Accordingly, cannot be attributed to the addition of human mean life completely the achievement that western medicine research and contribution. The improvement of human health condition also is not its contribution completely.
Be what reason is brought about long-term since cannot a lot of diseases treat this kind of condition effectively? Be we study in biology medicine the investment of the domain is inadequate? World each country research for biology medicine devoted capital total is as high as on one billion two hundred and fifteen million seven hundred and fifty-two thousand one hundred and ninety-two dollars every year, only American government invests two dollars every year, the investment that should say opposite content medicine has been in world front row. It is the scientist that pursues biology medicine research not quite clever, try hard not quite? The student that is admitted every year by American medicine school is achievement very outstanding student; is in the United States each research organization, university and biology medicine company are engaged in biology medicine considering advocate grind personnel has a doctor‘s degree, the << of journal of international authority science that has sufferred terminally of necessary professional training; is natural >> << science >> on published article has 1/2 to come the paper; that 2/3 is research of concerned biology medicine has two nobel prize every year at least in last few years (medicine and physiological award and chemical award) . This shows, the scientist great majority that pursues biology medicine research is the elite of bound of current science and technology.
Medical research is a science that explores human life rule, its ultimate goal is to defy disease and death, stimulative health is mixed improve life quality. Medical research to have its distinctive theory, thinking means and technical measure, but the ultimate goal that should achieve conquer disease, medical research theory and thinking means must accord with the objective law that disease happening develops, and should correct mistake and ceaseless innovation ceaselessly. The western medicine that by Wu Yimei the country is a delegate research to existing blemish, violated the essence of the disease and objective law, caused a disease consequently since remedy is long-term backwater not before waste with many manpower financial resources and time. If do not correct these errors as early as possible, the goal of conquer disease will leave us more and more distant, more and more Yao cannot be reached. Believe to be before this, a man of insight of domain of medicine of a lot of biology has discovered this problem, but why station of big wrist of bound of medicine of neither one biology comes out disclose defeats this piece of flimsy, be " is source body in this hill " ? Be still self interest place? The new clothes that Europe has a famous fairy tales to call << the emperor >> , admit against one‘s will to be worn on bare imperial body by force of imperial despotic power when great majority people when writing beautiful new clothes, only a fancy-free boy spoke the truth: Before the " of flowery " new clothes that delicacy of solid Piao Fu cuts hurry into parts to cut brandish into parts to write? to study in the western medicine that is a delegate with the United States, hope not only one however more fancy-free children can speak the truth. Does western medicine consider to in what blemish be put after all? How to correct these flaw? The author will be mixed theoretically from research train of thought, research technique, study the team is formed, reach the respect such as new drug research and development to try to discuss.
1. machinery is reductive theory---The theoretical foundation that western medicine research and chains
The west is the birthplace of contemporary Industrial Revolution. Steamer, electric lamp, phone, car, the train, the invention of plane and computer and the development of mechanical production industry brought the change of world-shaking to the world, but what study scientificly at the same time is mechanistic also produced far-reaching effect to the development of almost all science. In medical research domain of the United States, be affected mechanisticly by Wu Shou and often be person definition a machine. Like thinking human body resembles a machine, be by each component (organ, organization, cell, albumen and gene) what assemble and become. When machine occurrence breakdown, the component that should find that damage only changes it can make the machine returns to normal. Because this is considering to be abided by adamantinely on train of thought reductive talked theory, it is the athletic form end of life mechanical movement form, the law that uses form of elementary mechanical movement replaces the rule of form of advanced life motion.
This kind of machinery is reductive the soul that talked analytic method is western medicine, it thinks, all sorts of biological phenomena are OK by reductive into main unit, each are basic and unit each other are independent, do not change its essence because of explicit element. Carry unit to these research, can figure the essence that gives life campaign and metabolic rule. On research method it passes anatomy, histology, the technology such as biochemistry and molecular biology way general human body is reductive the organ that is independence, organization, cell, albumen or gene, the hope carries pair of single cells, the research of albumen or gene finds out influence life motion curve (cause a disease namely) the tiniest the most distinctive biology changes. In the diagnosis of the disease and remedial respect, also on the focusing change at element of single live thing, think every are planted the happening of the disease only by element of single live thing (albumen or gene) unusual change is caused, this element controls the disease process that writes the others, want to search this element only, reappearance exhibits a kind of corresponding medicaments to defy can cure a disease.
This kind of machinery is reductive the field of infection sex disease that talked medicine researchs to thinking kind is making do a bacterium to bring about has certain effect really, because the pathogeny body of these diseases is onefold bacterium normally, should pass only clinical examine obtain diagnose, use corresponding antibiotic to be able to cure a disease. Be able to bear or endure as the bacterium however the development of property of a medicine, the curative effect of antibiotic also is challenged austerely, a lot of antibiotic had been able to bear or endure to generation the bacterium of property of a medicine loses curative effect. Sooner or later, antibiotic can lose his completely because of this to fight infection action. Very lamentable is, mechanical and reductive talked medical research technique is coping with common disease (heart disease, cancer, the head is apoplectic wait) the disease that causes with virus infection (flu, avian flu, SARS, AIDS) the respect appears pale however be without as, the pathogeny because of these diseases and manage of hair interpretation of the cause are very complex, the change that is onefold pathogeny or element of single live thing far from can explain.
The fundamental flaw that western medicine research depends on ignoring the integral sex of life, the ego adjusting control of the mutual and associated sex between biology element and airframe (defence rehabilitate) ability. Research experience of a few years and clinical practice already proved, the disease is a very complex change process, each disease involves the human gene number that already verified at least (2-2.5 10 thousand gene) 1-2%(namely 200-500 gene) . Be opposite according to the author system of acute central nervous (head and spinal cord) the discovery in gene expression research of injury, in all 300 many different gene produce clear expression to change after injury. The mutual join access that carries these pair of gene undertakes integrated analysis, discover element of these hundreds biology was joined a bigger biology signal is delivered adjust network. The because element of many living things is unusual,changes place to cause network of whole live thing balance after scar is maladjusted just be the real reason that brings about nerve cell to cannot go against death. The happening that so numerous biology element shares a disease develops, if abide by the tradition of western medicine to study train of thought and remedial method again, will study key focusing only the certain at disease of be involved in is main biology element, repass develops the single remedy that is aimed at element of this lifetime content to treat a disease is the job that finishs impossibly apparently, this also is to come for years the main reason that a lot of diseases get effecting a radical cure hard. Because this machinery is reductive,talking is the chains that limitative medicine develops, the remedial step with the reason of hair interpretation of the cause that it explores a disease to us and significant progress has produced serious block up effect, if do not break this chains, the mankind conquers the end of the disease never will come true possibly.
2. take a part of the whole- - the blindness of western medicine research technique and limitation
China has an idiom to call " take a part of the whole " . A few blinds feel fokelore an elephant, those who feel a leg say elephant resembles a post, those who feel body say elephant resembles a wall, those who feel a tail say elephant resembles a snake, those who feel ear say elephant resembles a fan, because every blind just believes his personal feeling and experience, be not accepted or believe the feeling of others and viewpoint, because this is bigoted, vexed. Because of,use an analogy eye shot confine, not comprehensive to thing understanding, produce one-sided observation verdict consequently.
If give birth to the hair of the disease mechanism analogy to be an elephant, american type medicine research the job can call research of mood of take a part of the whole. Because it abides by machinery completely reductive talked research thinking way, the pathology foundation the disease and manage of hair interpretation of the cause are reductive disclose the change that is element of single live thing. No less than will be whole elephant breaks up different share, by lots and lots of research task group and researcher part to undertake feeling elephantine the job to each parts, some feels a leg, some feels body, some feels a tail, return some to feel ear. They are felt very seriously, very meticulous, very thorough also, almost they should feel every fine hair on the human body of the place or pore to be felt quickly. It is OK to feel new large " fine hair on the human body or pore " patent application or the paper is published on international tip magazine, the paper that touchs small " fine hair on the human body or pore " also can be published in general magazine. But this kind of " feels elephantine " to work to try hard to exceed investment more, further and further however from the panorama that masters " elephant " , more and more the waste that makes material resources of a kind of manpower and time. The research conclusion that reachs because of it is subjective and one-sided, do not have too much help to understanding the full view of " elephant " .
The field researchs in the central nervous scar with author familiar place, there is group of task of 400 many researches to undertaking this kind of " feels elephantine " job in the United States only, "Cell of the nerve after domain of the " that feel an elephant involves scar respectively dies, inflammation and should stimulate response, ionic balance is maladjusted inside the cell, signal is conducted, cellular cycle adjusting control is unusual, cellular structure is unusual, nerve denaturation, medication with correspondence etc, the biology member that feels also achieves nearly 200. Element of single live thing of every " fine hair on the human body that research task group is certain he is felt or pore "() it is unique, it is newest discovery, think to want to continue to be felt only can find effect a radical cure the therapeutics of specially good effect of central nervous scar, because this refuses,admit the " fine hair on the human body that someone else feels or pore " . However, because feel,be full of the hope of scar of conquer central nervous to new " fine hair on the human body or pore " as people again and again, medication because of what be aimed at " fine hair on the human body or pore " again the again and again fails and was full of disappointment. In the light of the " of other disease the " that feel an elephant works basic also and such, this is the true portraiture that medicine of current United States research to work, also be the mankind the distress in respect of antagonism disease menace. So far, the research of type of this kind of take a part of the whole still still is continueing, have the power that does not feel all " fine hair on the human body or pore " not to place a hand greatly. Two ambitious scientific plans offerred in government of 60 time United States: Dead lament of Huang thorium live abroad steals the? that record Ping another is conquer cancer plan. Be less than 10 years of time, the mankind ascended a moon successfully, but so far, went 40 years, we manage even the hair interpretation of the cause of cancer to did not consider to be clear about, cancer of conquer of prep let alone. This also from explaining the United States develops a field in machinery on the other hand is ace really, but exploring life rule aspect is a blind however. Unsuccessful prime cause is American medicine researcher dare not violate machinery from beginning to end in research reductive talked theory and thinking means, go up in research technique the exploration approach that uses formula of take a part of the whole.
The hair interpretation of the cause that should know an ill in the round manages, find truly effective treatment method, we should stop the medical research technique of type of this kind of take a part of the whole. Modern medicine had developed hundreds years, "The majority " fine hair on the human body of elephant " or pore " had been felt almost. Present problem is, how be each partial conformity of " elephant " a whole, let people understand the full view of " elephant " , this ability is the only way that develops effective treatment method.
The research team with unbalanced 3.- - the medical research of biologist dominant United States
Learn according to medicine of American experiment biology (the statistical figure that FASE announces, in the scientist that joins this society, 69.6% study a doctor for biology (Ph.D) , 19.2% for M.d. (MD) , only 8% for double doctor‘s degree (M.d. adds biology to study a doctor) gainer. By learning at this is institute of the United States‘ biggest biology medicine research, its include to physiology research a society, biochemical research learns and the branch such as pharmacodynamics and institute of experimental cure research learns, contain covered field of most biology medicine. The compositive structure that its member formed a structure to basically represent the scientist that biology medicine is engaged in studying the work in American universities and colleges and research organization and professional setting. Occupy an author additionally national to the United States wholesome academy (NIH) cancer institute (359 of NCI) advocate grind personnel (scientist of above of task group leader) degree setting analyses discovery, 65.5% study a doctor for biology (Ph.D) , 23.9% for M.d. (MD) , only 10.6% for double doctor‘s degree (M.d. adds biology to study a doctor) gainer. By at cancer institute it is an institute with the largest academy of American national sanitation, also be get a the most close together institute with clinical connection, the medicine that its talent structure shows to biologic scientist is in the United States is holding dominant position in research.
We know, m.d. is the professional public figure that has gotten systematic foundation medicine and clinical medicine training in school of college of medicine, their special skill is medicine (include fundamental medicine and clinical medicine) . And biology research the doctor is in domain of biologic division some (be like zoologic, botanical, biochemistry, molecular biology, microbiology, materia medica, or organic chemistry) the professional public figure that has gotten specialized training, the biologic knowledge that they have some side is good at at the biologic technology of one (like biochemical technology, molecular biology technology, or the) such as medicaments synthesis. Although biology and medicine are having very close connection, also can say the main base that is medicine, but from substantially it and medicine are having strict distinction.
Research target of medicine is the diagnosis of human body disease and cure, research target of biology is to move floral to grow, development and evolution. In recent years, be introduced as biology technology medical research, many biologist also enters medicine to research a field and gradually dominant medicine research. The research domain in him place special skill made these biologists that have research doctor‘s degree really very large contribution, also arose to urge action certainly to medical development, but train by the medicine that had not gotten comprehensive system at them, the objective law that develops to disease happening and mutual connection lack clear understanding, the biologic domain that accordingly their contribution is restricted to be familiar with at oneself only, contribution of ill to exploring the integrated hair of the disease mechanism is not large. For example, an element biologist is right molecular biology technology (be like DNA Sequence, isolation, purification, northern Blot, southern Blot, RT-PCR, proteinelectrophoresis) very perfectness, the target that research to place (some albumen and gene) very familiar also, but developing action and the mutual couplet with the disease happening in the disease to studying a target is however utterly ignorant, also do not know to study the change of the object can produce what kind of pathology physiology change. A lot of China doctoral students that undertake in the west biology medicine research and postdoctoral have a such consensus with visit scholar: of χ of border of male agreement drought sees? of beautiful jade of E know well divide outside studying to oneself the domain is very perfectness, know nothing about other domain, its special skill is to have fore-and-aft research, and the transverse connection that has a thing without ability.
Be what reason is caused does medicine of biologist dominant United States study this is planted today situation? In academy of American national sanitation (at the beginning of NIH) holds water, mix to make sure what medicine research is directional effectiveness, this academy made a provision: ?Institute Director) of of of gram of core of the greedy for food that confuse solder and each lab director (Laboratory/BranchChief) must by double doctor‘s degree (M.d. adds biology to study a doctor) or M.d. degree gainer is held the position of, biologic research doctor can hold the position of task group leader only (SectionChief) or research scientist (StaffScientist) . By did not break through down to society for a long time to study to medicine investment decreases at medical research wait for market economy element, a lot of outstanding double degree doctors and M.d. choice enter clinical medicine to the domain becomes a clinician and do not wish to consider to serve as his profession with medicine. Cause a large number of medicine to consider to get the shortage of army day figure so, the leadership position that below this kind of circumstance a lot of biology study to the doctor holds medicine to consider gradually, become the dean of school of college of medicine and research organization, strong point or director. This changes the medical research of type of farther aggravate take a part of the whole, make medicine research more deviated from oneself research target. Tell honestly, biologic research doctor is mixed in opposite content technology methodological control and perfectness respect exceed M.d. really, but we should realise clearly, biology technology is a tool of disease of conquer of human understanding disease merely, is not final research target. Replace a goal with the tool, can make with research of biologist dominant medicine medicine research only deviate orbit, make the end of human conquer disease more far.
4. is onefold medication disease---The job that never finishs possibly
The place before be like is narrated, get machine reductive the impact that research research thinking, when American researcher is studying the hair interpretation of the cause of the disease manages focusing at the element of single live thing that concerns with the disease (albumen or gene) on unusual change, this member is being held after should discovering some biology element produces apparent change is the culprit that causes a disease, seek corresponding remedy consequently (depressor or intensifier) go defying this a member. The policy that means of this kind of thinking and research theory affect service of American medical treatment and management department of medicines and chemical reagents inevitably and code are made. For example American medicines and chemical reagents and food management board (FDA) regulation, approve single remedy only commonly or most the clinical try out of medicine made of two or more ingredients of two kinds of pharmaceuticals, the compound prescription that does not encourage medicaments of two kinds of above enters clinical try out, reason is medicaments of two kinds of above is compound use the noxiousness side effect that adds medicaments likely. If want to have remedy of two kinds of above the clinical try out of compound prescription, the validity that must undertake much experimentation will prove single remedy first and avirulent sex side-effect, next the compound prescription after reoccupy experiment will prove to add has remedial effect and security as much.
Here whether does the compound that we do not discuss medicaments of two kinds of above first add noxiousness side effect for certain, discuss single remedy to whether can treat a disease effectively first. Come for years, the manpower material resources with old pharmaceutical factory and each medical company much investment and financial capacity undertake the west the research and development of hundreds of kinds of new drug, but after these medicaments enter clinical try out, or discovery does not have curative effect to the patient, or produces the noxiousness side effect that makes a person anxious. Coverage of not long ago confirms, of research and development of American Pfizer company fight arthritic medicines- - COX-2 depressor kind anodyne (Bextra and Celebrex) are prohibited continueing clinical try out, because of them not only indemonstrable have special curative effect to arthritis, can bring about the swift as the wind in heart disease and head to make instead, cause patient death even. Connect the ace product of Pfizer company research and development- - Wei elder brother (although Viagra) erects to male sex functional obstacle has curative effect, but because can cause heart disease,also be used by limitation. So far, outside dividing antibiotic to be able to control a bacterium effectively to contract sexual disease, still do not have a kind of specific to be able to treat a disease effectively.
The crisis that the failure that what reason causes again and again of new drug research and development and pharmacy industry produce ceaselessly be? Germ is medicine of American type west research is existing blemish. Long-term since, western medicine research human body the definition is a machine, identifying humanness body occurrence disease to appear as the machine is You Mou like breakdown place of 10 components attaint is caused, the component that should find this damage only repairs it, the machine can work afresh again. Accordingly almost all medicine study the element of odd lifetime content that focusing causes a disease at searching, and medicationing also is around move the element of single live thing that how antagonism happening changes and spread out. Ground of one‘s own wishful thinking thinks, a kind of disease can use treatment of a kind of specific, not was necessary to also cannot use medicaments of two kinds of above to have compound treatment. Theory of this kind of research and practice are affecting what American medicine learns policy and code deeply to make undoubtedly.
The fact proves, the code that restricts compound medicaments to use violated the objective law that disease happening develops completely. Because the disease is a complex pathology change process, what it won‘t cause the change that also won‘t cause element of single live thing only by the change of element of single live thing only, the development process of the disease should be the biology inside the cell the unbalance process of molecular adjustment network. This adjusts network by by tens of thousands biology element (albumen or gene) be formed, the big big a wide place in the road that these biology elements live as us, join together each other through be similar to the biology signal of highway and railroad to deliver route, form the biology inside a complete cell molecular adjustment network. Below normal circumstance, the position that all biology element is maintaining relative stability (namely not heighten does not reduce) again, maintain the relative balance of whole network consequently, this kind of relative balance is human body cell and the main base that the organization develops normal physiology function.
After disease happening, tens of even hundreds biology element produces corresponding change accordingly (some heighten, some reduces) , destroyed the relative balance of whole network system thereby, although the counteractive mechanism of human body oneself also tries to restore the balance of the network ceaselessly, the range that is like the network unbalance that the disease causes is too big, intensity is too strong, exceed the repair capacity of oneself, criterion network unbalance will develop toward not reversible direction, cause a cell finally death and organization are necrotic. And those who be aimed at element of single live thing medication can adjust only one of countless biology elements that change by disease place, although this kind adjusts very effective to element of corresponding single live thing, can change the active of this biology element and working position, also meet because of this part ground improves cellular biology the function of molecular adjustment network, but the normal balance that does not restore whole network effectively. This is great majority single remedy can alleviate only symptom and cannot effect a radical cure the likelihood of the disease reason. Terrible is, the active that changes element of single live thing and working status (break this biology molecule e.g. block) inevitable meeting is changed to it the working status of relevant other biology element and corresponding signal transfer access function, did not get resumptive evenly in cellular network, normal physiology function is put below the circumstance of the obstacle, can bring about the obstacle of other cell function instead, aggravate is whole the unbalance of cellular network, this is single remedy sometimes not only the likelihood that disables to be able to produce noxiousness side-effect and complication instead reason.
Came 1988 through be opposite the single remedy curative effect with the apoplectic head of 95 kinds of cure that passes in the try out on animal model during 2004 undertakes evaluating, the average and significant percentage that the author discovers to these medicaments reduce a head to injure constituent capacity is only 37.8% , that is to say the area of cerebral tissue damage of 62.2% still exists, single remedy can not produce the remedial result of 40% only at most, basically be short of hematic loss to do not have too great help to treating a head. And group of a few research uses the United States head of cure of compound of two kinds of chemical remedy is injured (if NMDA suffers body Jie to fight agent Memantine and Clenbuterol of adrenal intensifier accepting put oneself in another‘s position compound use or Methylprednisolone and BDNF are compound use) , can make the head injures constituent capacity to decrease 49, the 7% athletic functions that improved a head to injure small white rat apparently. The conditioning agent that the signal inside many cells uses to transfer network node gene when the author is considering to treat the new-style and compound medicaments that central nervous system injures (depressor or intensifier) make up compound medicaments cocktail. This kind of cocktail makes education cell is short of blood the surviving rate of 24 hours after anoxic injury is amounted to 80% , the bring down rate that organizes a capacity to damage of small rat brain also is achieved 72% . These experimental result specifications are onefold medication the disease has very big limitation, impossible from go up at all achieve the goal that cures a disease. If continue to count on,through research and development single remedy treats a disease, can be the job that never finishs possibly only.
About the noxiousness side-effect problem of medicaments, we must understand medicaments to produce the postulate of noxiousness first. Any medicaments (no matter Western medicine still is Chinese traditional medicine) the use dose with should exceed regular only can produce noxiousness, form harm to human body. Even the vitamin with indispensible human body also is such, for example excessive takes vitamin E to cause heart disease possibly. The experiment research to discover, become two kinds or medicaments of two kinds of above is using effective treatment dose (namely the smallest dose of effect of therapy of single remedy generation) below the condition compound use its noxiousness can increase really. This also is American FDA thinks of medicaments of two kinds of above compound use the basis that increases noxiousness side effect likely. But, when wanting us to reduce the dosage of medicaments the 1/2 that treats dosage effectively or 1/4 only, of medicaments of two kinds of above compound use not only enhanced curative effect to reduce medicaments noxiousness instead. The compound remedy that the author uses method of conpatibility of medicines of this kind of medicaments to make up a variety of conditioning agent system of remedial central nervous to injure is cocktail, this kind of cocktail not only have obvious remedy effect and noxiousness side-effect greatly under the single remedy that uses effective treatment dose. The clinical practice of compound prescription also proves same Chinese traditional medicine, want to control medicaments dosage correctly only, a few kinds even of ten kinds of medicaments compound use and won‘t produce noxiousness side effect. The dose that because of Chinese traditional medicine of medicine made of two or more ingredients the dosage when conpatibility of medicines often uses alone under unit drug, before doing not have conpatibility of medicines, the unit drug of such dosage is effect of short of therapy. The effectiveness of pharmaceuticals medicine made of two or more ingredients is combining the function after forming whole each other at them.
And a few accepted for poisonous medicaments, the use that should control them scientificly often can produce the magical curative effect that expect is less than after dosage, the Hong Kong that suffers cerebral scar because of traffic accident in England for example is defended inspect compere bang to be like a lady, announce her when British hospital already after cerebral death is cureless, it is Chinese traditional medicine makes her bring the dying back to life, and the ace Chinese traditional medicine that delivers her is An Gongniu yellow pill. This kind of An Gongniu contains Zhu Sha in Huang Wan (namely mercuric) , its have apparent noxiousness to human body. If press the standard of American FDA,this kind of medicine cannot be entered for certain clinical, but the clinical practice that is in China has proved An Gongniu yellow pill not only have distinct curative effect, what also do not have a lot of United States research and development is individual the noxiousness with new serious in that way drug and side-effect. Additional, be located in Shanghai Zhang Jiang the China of high-tech garden area uses arsenic one kind when protection and development academy not long ago just developed Chinese traditional medicine of classical traditional Chinese medical science (3 oxidation 2 arsenic) the new treatment that treats AIDS, also produce the peculiar curative effect that expect is less than, and its poison side-effect can be controlled arrive the smallest. Arsenic is accepted bane, large dose is taken cause death necessarily. But control its correctly to make dosage can treat a disease however, benefit at the mankind, this consolidates the rule with respect to the differentiate card that is a thing. Because of medicaments of these two kinds of above compound using those who add medicaments noxiousness side effect to conclude is very one-sided with the objective law that violates science.
5. medicine revolution---The turning point with powerful the Chinese nation
Nearly hundred years come, the change quickly of science and technology makes human society produced profound change, world each country realises new and high science and technology is to make the mankind progresses, economy grows, the real motive force with powerful nation. Who mastered advanced science and technology, who mastered future, mastered the world. The western medicine that by Wu Yimei the country is a delegate research to existing blemish, make the mankind is in passive position in the fight of conquer disease, wasted financial capacity of a lot of manpower material resources and valuable time, be these mistakes and blemish however the powerful nation of biology medicine science and technology that becomes future for China offerred precious opportunity. We should admit, make in machinery, the computer reachs IT, medicine diagnoses a technology, the respect such as development of medical apparatus and instruments, the United States and country of a few wests are already banner at China, but in medicine research and disease treat a field, china and United States still are in same scratch line to go up, and the United States still is carrying " machinery on the back reductive by " this heavy burden, beetle is worn " of " take a part of the whole this crutch. If can first start of a race, lead revolution of a medicine, china will become world medicine powerful nation completely likely. Once wait for the United States to realize his error, put down package and crutch banner start of a race, china should chase American general to must pay the price of special hardships again.
Experience for years in the United States according to the author, the United States is the country with very strong capability of an ego error correction, its error correction ability comes from the adjustment of market economy, after the error that realizes oneself research a field in medicine, the action that it can carry economic lever very quickly (if change investment, study fund, product production and the way of going from place to place that the market throws) correct an error, make science research to develop toward right way. Notable is, academy of American national sanitation (the policy of biology medicine research of its director United States and research foundation) already studied at medicine of a biology was being started by 2003 route chart plans (NIHRoadmap) . The core of this plan is: Ji core of а of Mo cellar chops? of Gong arm front is clinical. Use new biology medicine technology to study the whole of the disease changes, encourage new research thinking, encourage technical innovation, expedite the research and development of new drug and clinical application. The issue that this shows to the United States also realizes him to exist in biology medicine research, begin to change its biology medicine to study policy. But the United States should drop a load completely, desertion crutch still still needs time a few years, this research in medicine for China the domain precedes start of a race offerred opportunity. To hold this once in a blue moon historical good luck, the medicine that the author suggests to just face China in the following research to undertake enrich and adjustment:
1) . The talent is fostered
Train double doctor energetically (M.d. adds biology to study a doctor) talent, the medical knowledge that makes they master comprehensive system namely masters sophisticated biology technology again, attract them to enter medicine to research a field with market economy shift at the same time, go direction of dominant medicine research, lead medicine to study a team. Of reasonable control M.d. and biologic research doctor yield, study in medicine the condition that did not obtain a breakthrough falls, clinical cure also won‘t have apparent progress. Because the education of this M.d. is main,the complement of clinical public health worker mixes with a view to change, make sure job of cure of daily medical treatment is begun effectively. Study to biology the doctor undertakes billabong, in the research team that attracts the biologist that research to concern with the disease double doctor medicine to study the expert is led, produce their biologic special skill and effect adequately, but cannot let a biologist go in that way like the United States dominant medicine research. Cannot produce the biologist‘s effect namely otherwise, block up medical development. The biologist that pure to be engaged in biology research, should encourage them to enter special biology technology institute, the biology department of company of biology science and technology or university goes be engaged in concentrated biology technology studying development and education work. Developing him person with ability while, create all conditions to attract of all kinds study abroad personnel goes back to the motherland service, pay attention to particularly attract double doctor‘s degree is obtained in abroad (M.d. adds biology to study a doctor) talent, or the talent that acquires medical degree to obtain biology to study a doctor in abroad again in China goes back to the motherland, the nuclear mental efforts in letting them make research team is measured and get military thing.
2) . Study way
The way that medicine research must face towards sickness make a diagnosis and give treatment, front is clinical. All research should closely around move the integral sex that explores a disease and spread out, the hair interpretation of the cause that is a disease mainly manages, diagnose and treat. The dispersive sex that prevents type of American take a part of the whole research with free selection of subject. In initial stage, we can choose disease of a few acute (like scar, chemical and toxic, the urgent sexy disease that catch a gender) undertake tackling key problem, the mutual connection of element of the biology in studying acute disease produces development process systematically in the round and colony change and whole cell adjust the change of the network. Choose acute disease to undertake tackling key problem first, because the animal model of acute disease duplicates more easily,be, come on time is shorter observe easily. The biology element that causes in ascertain acute disease and cell adjust after network whole changes, we can master the basic rule that disease happening develops and pathology foundation, it is chronic illness thereby (if heart disease, cancer, head is apoplectic,wait) research lays important foundation. Although the pathogeny because of urgent chronic illness is different, but the disease change process on the human body reaction to the disease and cell and molecular level should have certain intercommunity and similar sex. On specific research technique we can take the technical approach of " of " integrated medicine, comprehensive systematically collect is concentrated the information of the biology element of the disease and its signal access, build the database of information of medicine of computer live thing of this disease, of all biology member that with the computer analytic collect reachs and its signal access hand in collect connection, find out the join node in their join network and network, develop experimental treatment as drone with these join node then. On technical approach, applicable biology chip (gene and albumen chip) the member of big range biology with technology and new other determines the gene group that the technique goes studying the disease is caused, the integral change that albumen group and signal pass access and element of the biology inside the cell after the experiment is treated adjust the reaction of the network.
3) . Medicaments research and development
In respect of medicaments research and development, should be encouraged and promote the live thing inside cell of can effective balance the compound medicaments recipe of molecular adjustment network and Chinese traditional medicine the development of prescription. Medical practice has proved, single remedy treats a disease effectively, use adjust what network of element of the biology inside the cell balances is compound medication the method just may be the accurate method that cures a disease. Examine the standard with new drug whether successful research and development is: ? of arm of duckweed of acute communicable diseases of Yi travel е does not have apparent noxiousness side-effect to human body, is not the assorted amount of medicaments. The medicaments government laws and regulations that making China respect cannot overall copies the United States and western country all regulations systems and legal laws and regulations. American is not an immortal, they also are being explored ceaselessly, innovate ceaselessly, ceaseless generation is wrong, correct oneself error ceaselessly again. We object extremely arrogant, firm condition is self-given, but also cannot worship foreign things, overall is westernized. Cannot think all American things are the most advanced and best show, cannot think to conform with the world even if imitate the United States and western country more all law system, thinking means, organize structure and scientific research method. Human society is in ceaseless progress, science also is developing ceaselessly. Although China has the place that is inferior to the United States, but the place that also has excel United States, for example the most reasonable cure principle on the world of the doctor of traditional Chinese medicine before treating a principle to look namely. Although theory of doctor of traditional Chinese medicine is put in the flaw with serious move, cannot explain a lot of physiology pathology inside human body change scientificly, but by Wu Zhong cure theory is built at thousands of years before, science and technology is underdeveloped at that time, a lot of clinical phenomena can be used only a few have mysterious colorific doctrine to try to describe, create a traditional Chinese medical science to the person unscientific not rigorous impression. However remedial method of the doctor of traditional Chinese medicine and the practice that the principle passes a few chiliad examine to already proved to have its rationality, because it accords with the essence of the disease and objective law basically. Any thinking always the viewpoint that Chinese thing is inferior to the United States necessarily, it is the clammy expression that loses self-confident heart to oneself.
4) . Study policy
Medical is the science of a ceaseless development, examine medical research is correct, whether significant exclusive level is to see it whether announce correctly the mechanism of the disease, whether the remedial step with significant progress, whether the health that improves the mankind truly. is not to look publish how many paper, have how many honor, there is how many flowery aureola on the body. The field researchs in the science that explores sealed world, only seasoned person the cent of the person that lack with experience, without alleged an academic authority. The field researchs in medicine, american is not, also do not have the adviser that the qualification is a Chinese, can calculate the loser that has experience only at most. When accordingly the government sector is making medicine study policy, the lesson of should referenced United States and the experience with western successful country and failure, but cannot the thing that overall copies abroad (because biology medicine of the United States research policy and code also are in,change) ceaselessly, want to make the regulations system that suits medicine to study healthy progress, legal laws and regulations, organize structure and academic system, creation gets used to new relations of production to it. Should make full use of for example the constituent capability with Chinese very strong government, the main disease with healthy to minatory mankind tissue (heart disease, cancer, the head is apoplectic, AIDS, scar and all sorts of epidemic contagion) undertake those who have specific aim tackle key problem, the key gives to give aid to in research and development funds respect. Set relevant research task group for standard reset with the disease, configure a certain quantity of clinician, biologist, chemist, mathematician, physicist and computer expert. Study resource and scientific research funds to avoid to seldom count person forestall, in the light of the task of same disease research group should have many, make them mutual compete, preferred clean out bad. Study in same task the tenure of office that academic leader should fulfil in the group is made, it is a lieutenancy 5 years, if progress is obtained to be able to be connected on research,hold the post of, but if make progress to change through making public invite applications for a job without research,cannot exceed two; at most academic leader. This kind of lieutenancy makes the creativity that will make whole research team keeps active from beginning to end. Studying train of thought, academic theory and technical measure respect, should not deviate from only total research target and direction should encourage innovation, encourage competition, encourage free development.
If say Europe is the center of Industrial Revolution, the United States is the center of information revolution, china should have determination to become the center of medical revolution. This medicine revolution will get effecting a radical cure completely is a mark with the common disease of health of a few minatory mankinds. The Chinese nation is one clever with the nation that has creativity, want us to grasp an opportunity only, break a tradition, be brave in to go all out in work, regular meeting becomes powerful nation of world biology medicine.
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