Headachy medical research general situation

Medical Apartheid Part 1

Headachy medical research general situation Author: Sulphur

EpidemiologyHaving a headache is clinical go up the commonnest symptom and one of action in chief, ever had statistic, because of pure the person that have a headache to see a doctor to nerve internal medicine, occupy the 30%-40% of gross seeing a doctor, serve as the person that neurosis will see a doctor in order to have a headache, occupy the 40%-50% of gross seeing a doctor, reason has have a headache symptom person, hold sum total of outpatient service of nerve internal medicine 70% one 90% ; Incidence of a disease of migraine whole world is 8.4%-28% about, american incidence of a disease is 11% , 1999, citizen of 28 million United States has serious splitting headache, other country also roughly identical. Our country occupies not complete count, the sicken rate of adult migraine is in 7.7%-18.7% , among them female patient compares male patient much 3-4 times. Crowd together sex has a headache incidence of a disease is relatively some lower.

Cause an element
Mood (nervous, depressed, angst) it is to cause have a headache all in all hurried sends an element, other and main inducement has fatigue and Morpheus inadequacy, excessive, season to change (especially wet, heat coexists) , endocrine change (menses) , medicaments (if enlarge is hemal commonly used and medicaments, demulcent medicine and stop spit amine of medicine, ergot) , and the environmental element such as noise, strong light, alcoholic beverage of the additional and unwell edible that spend the ground, coffee, chocolate bring about easily also have a headache.

Clinical cent
Have a headache to sending a gender formerly, newest (2004) international has a headache association classification standard is:

1, migraine belongs to sex of blood-vessel of the raw nerve that send a gender to have a headache one of, can distribute kind of kind again. Its characteristic is medium or spend again jump painful or beating painful, a side or bilateral and alternant ache, can alleviate by oneself, have a relapse instead, fit intermittence is not had have a headache reach positive aspect to ask for, along with the age growth has heal tendency.

2, nervous sex has a headache (TTH) , say flesh contractility has a headache again, point to bilateral the constrictive sex of occipitalia or full head or oppressive sex, it is chronic in having a headache the commonnest one sort, divide 3 inferior model: Push pound ⒆ to have enough lowing ⒏ sip smashs ⒆ attempt having enough abstruse  jumps over Zong to sentence Yun to bark crab of Can of ash standing tall and upright treats frame of street of  of be used to of ≌ of Xiang of  of Mi of buttock of  of be used to of ≌ of   Xiang

3, crowd together sex has a headache (the autonomy of CH) etc trigeminal nerve has a headache (TACs) belongs to blood-vessel of the raw nerve that send a gender to have a headache one of, divide again for 4 kinds of types. Its characteristic is concentrated (teeming) fit, acuteness, acute appearance of painful, explosion, be located in ministry of Nie of a side orbit, ball hind, forehead; Companion congests with film of side eye union, weep, block up nasally, shed tears to reach / or Horner syndrome. Crowd together sex has a headache is a kind of the mankind‘s most serious aching type probably. It is because of having a headache inside crowd together period concentrated fit, get a name consequently, weigh group of hair sexes to have a headache again. Crowd together period can count Zhou Zhi a few months continuously.

4, other type sends a gender to have a headache formerly. Include to send a gender to prickle formerly model have a headache, cough have a headache, labor have a headache, the former hair sex that concerns with sexual activity has a headache, sex of the headache that before falling asleep, happens, former hair explodes hairstyle has a headache, durative slant side has a headache, new-style and daily durative have a headache.

Pathogeny interpretation of the cause
Up to now painful pathogeny pathology still is not clear about medical correct, to migraine, basically have the following kinds of theory:

One, hemal source doctrine
Was being put forward to have a headache above all by Wolff 1963 is disease of the original blood vessel that send a gender. This doctrine basis is: What hemal and outspread agent and contractive medicine can come into being sex of change, beating to having a headache is painful as consistent as pulse photograph, apply pressure carotid with Nie shallow artery has a headache can alleviate. But from 20 centuries 80 time, RCBF, FMRI and PET research result shook the foundation of this doctrine.

2, nerve source doctrineThe change of function of the nerve when thinking migraine breaks out is principal, the change of hematic flow is afterwards hair, migraine and cortex diffuse restrain and nerve is given concern character. But the near future research to discover 4 kinds of intense nerve stimulate peptide Jie to fight an agent, remedial migraine is invalid, certainly still other element is participated in. Still research discovers 1/3 migraine patient no matter hemal dilate is former hair or afterwards hair, vasomotor agent can alleviate like ergot amine have a headache. Accordingly these research show migraine also cannot use nerve source doctrine completely to explain.

3, nerve blood-vessel doctrineThe hemal doctrine of migraine is contended for with what neurology says have more than 100 years. Moskowitz is in after report provoked trigeminal division 1984, discover putamen blood-vessel produces asepsis sex inflammation, think because trigeminal nerve is hemal,migraine is system (suffer body adjustment by 5-HTIB/ID) with blemish of function of system of analgesia of sex of the source inside central nervous system (concern with heredity) reach stimulation of overmuch inside and outside to cause. Offer nerve blood-vessel theory thereby, namely trigeminal hemal doctrine. At present this doctrine is in numerous doctrine, manage dominant position.

4, discovery of biochemical element research oxidizes in migraine patient nitrogen (HO) , magnesian (Mg2+ ) , much cling to amine and Gi albumen produce unusual change, chroma and symptom show correspondence, and these material flow inside the leakage outside albumen of the plasma on hemal to dilate, trigeminal fiber, stimulative calcium, biology energy metabolization effective, those who participate in migraine come on.

5, genetic element
Migraine is a kind have commonly familial come on the disease of the tendency. The gene as type twin migraine, familial sex hemiplegy migraine (Ch19p13) choppy, and what study discovery of late is much cling to amine β - hydroxide is changed enzymatic (DBH) easy sensibility of gene and typical migraine is had wait for a gene relation, these hint migraine may be disease of a kind of polygene.

Have a headache to also have a lot of theory to crowd together sex, although the name is different, but essence and migraine almost close. Regretful is all these doctrine all cannot explain independently have a headache the mechanism of fit.

Cure

Acute fit: Should attract a person instantly the oxygen of 100% and classics give 5-HTP excited dose hypodermically.

General processing:

Medication: Crowd together sex has a headache use ergot amine, vein to give the ground bazoo of Saimisong, lidocaine the person that exciting therapeutics reachs deep of drop law, head to be treated hard gives the operation is treated; Migraine often uses analgesia medicine and stop spit medicine operable, painful effect beautiful is spent in be opposite; The person that spend again can use Quputan kind medicaments, the effect relatively beautiful of ergot amine medicaments.

Medicaments precaution: Renouncing inducement is all in all precautionary measures. Migraine can be installed with the result, acid of third the fifth of the ten Heavenly Stem, calcic Jie fights Qin of benefit of agent fluorine laurel; Crowd together sex has a headache a gleam of fights an agent for calcic passageway Jie, second line is amine of methylic ergot acyl and acid of third the fifth of the ten Heavenly Stem. 3 lines are bazoo of drop of 10% cocaine solution.

The place on put together is narrated, although medicine research to have a headache nearly 300 years, but to the come oning that have a headache mechanism still is not clear about, also appear on cure be at a loss what to do, bring anguish of great body and mind and economic burden to the patient. A report with the closest World Health Organization will have a headache range causes one of chronic diseases with incomplete the strongest sex, will spend again have a headache one day of fit to be equal to break down at a day of limb, mental disease or gawkish those who cause break can. And have a headache can raise the occurence rate that the head straightens dead, raise the possibility that epilepsy comes on, reach the happening of disease of other head ministry.